99.42%COA›
GLP-1 & Metabolic
AP3-R
Purity 99.65%Min 10 vials per SKU (1 kit)
$23.00$32.20
1 kit — $230.00 per kit (10 vials).
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All vial caps are white and flip-off.
Third-party tested
HPLC + MS verified on every production lot.
Same day shipping
All orders received by 2PM ship the same day.
COA on request
Lot documentation available for every compound.
AP3-R (Retatrutide (LY3437943)) is supplied in 10 mg vials, packed 10 vials per kit (1 SKU minimum). CAS 2381089-83-2. Purity 99.63% by HPLC.
Description
AP3-R is our wholesale designation for research-grade retatrutide, a synthetic triple-receptor agonist with activity at the GLP-1, GIP, and glucagon receptors. Supplied lyophilized in 10-vial kits with 99%+ purity confirmed by third-party HPLC and mass spectrometry, and a lot-specific certificate of analysis available on every order.
What is Retatrutide (LY3437943)?
Retatrutide (development code LY3437943) is a 39-amino-acid synthetic peptide engineered so that a single molecule engages three metabolic receptors at once — GLP-1R, GIPR, and GCGR. Laboratories work with it as a reference compound for studying appetite signalling, energy expenditure, lipolysis, and hepatic lipid handling in preclinical models.
Key research applications
Metabolic signalling
Used to model how simultaneous activation of three receptors shifts energy balance in ways single-agonist compounds cannot reproduce.
Body-composition models
A common comparator in preclinical work on adiposity, food-intake behaviour, and substrate utilisation.
Glycemic research
Applied in glucose-tolerance and insulin-sensitivity assays alongside GLP-1 and dual-agonist references.
Hepatic lipid studies
Glucagon-receptor engagement makes it a tool compound for fatty-acid oxidation and liver-fat endpoints.
AP3-R specifications
- Amount
- 10 mg | 20 mg | 30 mg | 40 mg | 60 mg per vial · 10 vials per kit
- Purity
- 99.63%+ (third-party HPLC and mass spectrometry)
- Formula
- C221H342N46O68 | MW: ≈4,731 Da | CAS: 2381089-83-2
- Form
- Lyophilized powder
- Storage
- -20°C or below as a lyophilized powder; 2-8°C after reconstitution and used within the window defined by your protocol.
- Testing
- Lot PX1R10-0021 — COA-2026-EHTM8W, 99.65% purity by HPLC, tested 07/31/2026 by an independent ISO/IEC 17025 lab
- Origin
- US manufactured, third-party tested
- Presentation
- White flip-off caps on every vial
Research use only. Not for human or veterinary consumption, diagnostic, or therapeutic use.